“Escape mechanisms from antiangiogenic therapy: an immune cell's perspective,” Advances in Experimental Medicine and Biology (December 2013)

Co-authored and copyedited a review article on how glioblastoma multiforme (GBM), the most aggressive form of brain cancer, can bypass therapy designed to inhibit blood vessel growth, starving the tumor of oxygen and nutrients. In some cases, low oxygen turns on molecular pathways that promote tumor growth, including those that spur the development of new blood vessels.

 

"VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex,” Cancer Cell (July 2012)

Co-authored and copyedited a paper proposing a mechanism for the relapse pattern observed in GBM during therapy meant to inhibit the blood vessel growth protein VEGF. The mechanism involves a complex interaction between the receptors for the VEGF and c-Met proteins that triggers tumor cell invasion.

 

UCSF Department of Neurological Surgery 2011 Year in Review

Helped write content for annual newsletter detailing department research highlights

 

Tumor Microenvironment Network (TMEN) U54 Grant (January 2011)

Played key role in editing a National Institutes of Health grant application for $7 million to establish a multidisciplinary, multi-institutional research program to understand the dialogue between tumor cells and the brain environment in GBM